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Abstract Detail

Genetics Section

Zanis, Michael, J. [1].

Ecological and evolutionary factors shaping gene function during polyploidy.

Polyploidy is a powerful mechanism underlying speciation and diversification of plants. Polyploidy (whole genome duplication) also provides a rich substrate for the diversification of genetic pathways. Several molecular evolutionary questions remain regarding the evolutionary consequences and fates of genes in polyploid genomes. These questions center on the extent to which gene dosage, subfunctionalization, adaptive conflict, neofunctionalization, and pseduogenization play a role in structuring genetic pathways. Especially interesting is the role and contribution of ecological factors shaping the fate of polyploids and the evolution of gene function. We have developed an Individual-Based Model (IBM) to examine the evolution and ecological consequences of polyploidy and associated evolutionary genetic changes. The use of an IBM approach has allowed us to explore how spatial patterning of individuals in a population affects the formation and subsequent evolution of polyploids. Our model allows us to explore the consequence of modular gene structure and gene dosage concepts during the formation of polyploids. We link these molecular evolution changes to ecological concepts in an effort to understand the factors influencing polyploid evolution. Initial results suggest that in some instances gene balance can play an important role during the molecular evolution of genetic systems following polyploidy.

Broader Impacts:

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Related Links:
Zanis Lab Website

1 - Purdue University, Botany and Plant Pathology, 915 West State Street, West Lafayette, IN, 47907

Individual-Based Model
Computational biology.

Presentation Type: Oral Paper:Papers for Sections
Session: 1
Location: 556A/Convention Center
Date: Monday, August 2nd, 2010
Time: 9:15 AM
Number: 1006
Abstract ID:605

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